The fall of Tabriz after the loss at Chaldoran (1514 AD. / 920 AH.) paved the way for looting the major part of material and moral wealth of Safavid capital. Meantime, considerable number of artist elites of Tabriz had been transplanted to Ottoman territories. This compulsory migration transmitted the accomplishments of Safavid Tabriz Miniature School, the heir of artistic schools of Herat, Jalayerids, and Turkmen to the Istanbul School. Some of these miniaturists such as Sha Quli, the painter, and his students had created and flourished a new style called Saz. This research will review the historical events which are related to the transmission of Tabriz School miniaturists into Istanbul and study the role of these artists in formation of an evolution in the Ottoman miniature art.